CD38 and Miyoshi myopathy: This finding has made CD38 a target for therapeutic antibodies in MM, including daratumumab, a human anti-CD38 antibody that has been approved by the FDA both as monotherapy and in combination with standards of care, and isatuximab, a human anti-CD38 antibody that has recently been approved in combination with pomalidomide and dexamethasone [182,183].