HSPA5 and malignant colon neoplasm: In both breast and colon cancer cell lines, it was observed that while ATAD3A knockdown decreased the protein levels of GRP78 and WASF3, WASF3 levels could be ameliorated by overexpressing GRP78. Moreover, in cells overexpressing WASF3, the half-life of WASF3 could be significantly extended if GRP78 was also overexpressed.