It is reasonable to assume that protein degradation products can affect PPIs in a similar manner [190], whereby short peptides can affect cellular processes in a way beyond explanation at the current state at knowledge e.g. there are more than 1700 peptides (sometimes fragments of angiotensinogen) known to lower arterial hypertension [191]—the mechanism of their action is unknown. The gene discussed is AGT; the disease is Hypertension.