Cardiolipin-induced SUMOylation inhibits IL-10 production by lung CD11b þLy6GintLy6CloF4/80 þ cells because of the recruitment of a repressive nuclear receptor corepressor (NCOR)/ histone deacetylase 3 (HDAC3) complex to the IL-10 promoter, ending in persistent inflammation during pneumonia [156]. The gene discussed is IL10; the disease is pneumonia.