ETV6/RUNX1 t(12;21)(p13;q22), which often co-occurs with deletion of the ETV6 gene, is a typical rearrangement in childhood BCP-ALL, while in T-ALL, fusion-related signalling pathway or transcriptional regulation (ETV6/ABL1 and ETV6/CTNNB1) was observed [41]. Here, RUNX1 is linked to acute lymphoblastic leukemia.