While analyzing the M1 or M2 predominance in the different monocyte subpopulations, we observed an increase in the M2 CD14+CD16+ monocyte subpopulation (p < 0.001), as well in the M2 CD14−CD16+ monocytes (p < 0.05), in HD patients as opposed to the controls. Here, CD14 is linked to Huntington disease.