Then, assessing the expression of M1 (CD86 and CCR2) and M2 (CD206, CXCR3, and CD163) protein markers, we observed that, in comparison to the healthy subjects, HD patients showed an increased percentage of anti-inflammatory and immunosuppressive CD206+CXCR3+CD163+ M2 monocytes (p < 0.01), while the pro-inflammatory CD86+CCR2+ M1 monocyte population did not seem to be modified (p > 0.05) (Figure 1B,C). Here, MRC1 is linked to Huntington disease.