The majority of CD8+ T cells in all breast tumor subtypes are TEM (CD45RA−CCR7−; 72%), accompanied by a smaller group of TEMRA (effector memory CD45RA+, CD45RA+ CCR7−; 23%), and minor populations of TCM (central memory, CD45RA−CCR7+; 3%), and TNAIVE (CD45RA+CCR7+;1%) [23]. Here, CD8A is linked to breast neoplasm.