CD69+CD103+ T cells (TRM) are highly enriched close to triple negative tumor cells (e.g., inflamed-SI), CD69+CD103− CD8+ T cells are more evenly distributed between stroma and cancer cell islands (e.g., both inflamed-SI and inflamed-SR), and CD69−CD103−CD8 T cells are found almost exclusively in the stroma (e.g., inflamed-SR) [27] (Figure 1). The gene discussed is ITGAE; the disease is cancer.