The majority of the CD4+ T cells in all breast tumors are TEM (CD45RA−CCR7−; 88%), followed by a small group of TEMRA (CD45RA+CCR7−; 8%), TCM (CD45RA−CCR7+;4%), and TNAIVE (CD45RA+CCR7+; 1%) [23]. This evidence concerns the gene CCR7 and breast neoplasm.