A different genetic background is a possible explanation, since only one patient with anti-AChR positive MG was encountered, and the other two LESA-like TH patients with MG-associated autoantibodies did not suffer from EOMG: One patient at age 67 had non-thymomatous, anti-titin/anti-AChR autoantibody-positive late-onset MG (LOMG), while the other patient (without overt MG symptoms) had anti-MuSK antibodies. Here, MUSK is linked to myasthenia gravis.