Another study by Ta et al. showed that NF-kβ, constitutively active in pancreatic cancer patients, is promoted by miR-1290, relates to the expression of IKK1 [91], and is implicated in the downregulation of miR-146a, suggesting its role as a tumor suppressor in most cancers. Here, NFKB1 is linked to familial pancreatic carcinoma.