In an experiment using N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced PD mouse model, Zhou et al. [113] found that EGCG treatment restored the movement behavior of the mice impaired by the drug and prevented its toxicity in tyrosine hydroxylase-positive cells in the substantia nigra pars compacta region. This evidence concerns the gene TH and Parkinson disease.