Some of the 124I-labeled PET imaging pharmaceuticals based on the small molecule (with the target given in the parenthesis) are 124I-MIBG (adrenergic activity), 124I-IAZA and 124I-IAZG (hypoxia agent), 124I-dRFIB, 124I-IUdR and 124I-CDK4/6 inhibitors (cell proliferation), 124I-hypericin (protein-kinase C), 124I-FIAU (herpes virus thymidine kinase), m-124I-IPPM (opioid receptors), 124I-IPQA ((EGFR kinase activity), 124I-labeled-6-anilino-quinazoline (EGFR inhibitors), 124I-purpurinimide (tumor imaging) [151]. The gene discussed is EGFR; the disease is neoplasm.