CXCL8 and non-small cell lung carcinoma: A study of PC-9, a gefitinib-sensitive NSCLC cell line, investigated whether IL-8 was associated with resistance to gefitinib and found that, in addition to IL-8, an IL-8-specific receptor, C-X-C motif chemokine receptor 1 (CXCR1) was significantly upregulated in this cell line.