NUP98 and lung cancer: It was found that the translocation between chromosome 6 and chromosome 4, leading to the fusion of proto-oncogene 1, receptor tyrosine kinase (ROS1) to solute carrier family 34 member 2 (SLC34A2), drives lung cancer development [1], and the translocation-mediated fusion of the nucleoporin 98 kDa (NUP98) gene and topoisomerase (DNA) IIB 180 kDa (TOP2B) gene acts as a pathogenic factor in acute myeloid leukemia [2].