Other relevant enriched pathways with upregulated DEG included VEGF signaling pathway (RF = 0.18, padj = 0.003), pathways in cancer (RF = 0.17, padj = 1.12E-12), and neurotrophin signaling pathway (RF = 0.2, padj = 1.38E-6) (Figure 5A). The gene discussed is VEGFA; the disease is cancer.