Thus, GLP-1 might be in line with natriuretic peptides or interleukin 10 (IL-10), which are upregulated following inflammatory stimuli and predict adverse clinical outcomes in patients with myocardial infarction and HF, respectively, but remain protective as endogenous counter-regulatory factors [143,144,145,146]. The gene discussed is IL10; the disease is myocardial infarction.