In particular, the analysis revealed a possible reduction of BCL11A (BAF Chromatin Remodeling Complex Subunit; OMIM 606557) TFs reported in association with intellectual developmental disorder with persistence of fetal hemoglobin (HbF) including microcephaly, down-slanting palpebral fissures, strabismus and external ear abnormalities [19]. The gene discussed is BANF1; the disease is microcephaly.