Finally, a case report described a patient who developed refractory schizophrenia that mimicked an exacerbation of encephalitis with antibodies to GluN2B after administration of clozapine [40], thus suggesting the importance of differentiating between a diagnosis of refractory schizophrenia and encephalitis with antibodies to GluN2B. The gene discussed is GRIN2B; the disease is schizophrenia.