Finally, between 4% and 7.5% of patients with anti-NMDAR encephalitis have concurrent glial or neuronal-surface antibodies, with the most frequent association being with myelin oligodendrocyte glycoprotein (MOG) or aquaporin 4 (AQP4) antibodies, which result in overlapping anti-NMDAR encephalitis with demyelinating disorders [23,24]. Here, AQP4 is linked to demyelinating disease.