Apart from Adenomatous Polyposis Coli (APC) mutations, which occur in about 60% of non-invasive dysplastic lesions including adenoma and high-grade disease, but rarely in gastric carcinoma, molecular alterations in TubA overlap with those of gastric cancer: microsatellite instability (MSI) has been reported in 27% [15]. This evidence concerns the gene APC and gastric cancer.