TNF and hydrops fetalis: Clinical studies show that oral Chinese patent medicine combined with routine treatment can improve the clinical symptoms, exercise endurance, quality of life, laboratory examination, physical examination of HF patients.[21] In addition, QSYQ can lower the readmission rate of HF patients.[22] Experimental studies show that in the aspect of inflammation, QSYQ can relieve ventricular remodeling by inhibiting the inflammatory factor IL-6 TNF-α and related signal transduction pathway proteins.