Among the gestational metabolic changes, increased insulin resistance is observed during pregnancy due to an increase of gestational hormones, such as placental lactogen, cortisol, and progesterone.5These physiological changes are intended to guarantee glycemic support to the fetus.5Women develop hyperglycemia when increased insulin resistance is not adequately compensated for by increased pancreatic beta-cell insulin production.11 Here, INS is linked to Insulin resistance.