These preliminary studies were bolstered by the identificationof functional synapses between neurons and glioma cells, with transcriptomicanalysis further confirming that the glioma cells express GluA2, a subunit ofthe ionotropic glutamate receptor, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR). The gene discussed is GRIA2; the disease is central nervous system cancer.