Although we could not evaluate their differentiation into plasma cells or Ab production in mice after transfer, which are indistinguishable from host-derived plasma cells or Abs existing in far excess, inhibition of tumor growth and prolonged survival of APCmin/+ mice by the transfer of the TiBc-iGB cells are likely mediated by tumor binding of the Abs produced from the transferred TiBc-iGB cells via differentiation into plasma cells. Here, DDX41 is linked to neoplasm.