IL1B and COVID-19: Overall, various plasma cytokines and chemokines were reported to be deregulated in COVID-19 patients; these include TNF-α, interleukins (IL-1, IL-2, IL- 4, IL-7, IL-10, IL-12, IL-13, IL-17), macrophage colony-stimulating factor (MCSF), IP-10, MCP-1 (C-C motif chemokine 2, CCL2), MIP-1α, hepatocyte growth factor (HGF), IFN-γ, CCL3, CCL5 and many others [6].