In positive late infection group, three patients (6.25%) showed IgG anti-annexin-V antibody positivity (23.75 U/ml, 11.31 U/ml, and 20.87 U/ml); moreover, three patients showed IgM anti-annexin-V antibody positivity (16.25 U/ml, 11.37 U/ml, and 10.6 U/ml). This evidence concerns the gene CD40LG and infection.