Our recent work using three different types of aggressive lymphoma cell lines has shown that PRMT5 promotes WNT/β‐CATENIN proliferative signalling by transcriptionally repressing expression of pathway antagonists, AXIN2 and WIF1. 37Consequently, expression of WNT/β‐CATENIN target genes such as CYCLIN D1, c‐MYC and SURVIVIN increases.37 This evidence concerns the gene AXIN2 and lymphoma.