FBXO32 and melanoma: Using two different siRNA targeting FBXO32, in melanoma cell expressing high endogenous FBXO32 (cells from patient 2), we observed that the inhibition of FBXO32 expression (Fig. 3A) led to a decrease in the migration of melanoma cells in Boyden chambers assays as demonstrated by the pictures of the lower face of the wells (Fig. 3B) and by quantification of three independent experiments (Fig. 3C).