Among them, we selected those that (i) contained a ChIP-Seq-validated MITF binding site in their promoter [21], (ii) were correlated with MITF expression in the CCLE series of 61 melanoma cells (Log(2)FC > 1) (https://portals.broadinstitute.org/ccle/about), and (iii) were downregulated by siMITF (log(2)FC < –1). The gene discussed is MITF; the disease is melanoma.