Similar to their inhibitory activities against both wild-type HIV-1 and pseudotyped HIV-1 infections, the transduction of GPI-FluIgG03 did not impart cell resistance, whereas GPI-m36.4-transduced cells were highly resistant to cell fusion mediated by HIV-1 Env proteins with divergent subtypes and phenotypes (Table 2). Here, GPI is linked to HIV-1 infection.