Such studies are underway; in Scotland, patients reporting rectal bleeding (considered a ‘red flag’ symptom) in primary care with a f-Hb <10 μg Hb/g faeces were unlikely to be harbouring CRC or other serious bowel disease;30 similar results were observed in Sweden.31 Those will complement the study reported here, and establish the final place for FIT in colorectal cancer triage. This evidence concerns the gene GSTM1 and colorectal cancer.