Such studies are underway; in Scotland, patients reporting rectal bleeding (considered a ‘red flag’ symptom) in primary care with a f-Hb <10 μg Hb/g faeces were unlikely to be harbouring CRC or other serious bowel disease;30 similar results were observed in Sweden.31 Those will complement the study reported here, and establish the final place for FIT in colorectal cancer triage. The gene discussed is GSTM1; the disease is colorectal carcinoma.