IFNG and neoplasm: To this end, we first assessed the reactivity of tumor-infiltrating lymphocytes (TILs) isolated from untreated SMA560 tumors to 12 top-predicted MHC I-restricted neoepitopes (IEDB MHC I percentile rank score ≤0.4; Supplementary Table 1), which included Odc1MHC I, using the IFNγ ELISpot assay.