ANXA1 and neoplasm: For example, ANXA1 has been reported to be overexpressed in some tumour types, including oesophageal adenocarcinoma162, pancreatic adenocarcinoma163 and hairy cell leukaemia162, while ANXA2 is upregulated in breast cancer164, high-grade gliomas165 and kidney cancer166 (reviewed in ref. 167).