LMX1B and open-angle glaucoma: The LIM homeobox transcription factor 1-beta (LMX1B) gene was associated with elevated IOP and POAG through GWAS and has been validated in multiple populations (Choquet et al., 2018; Gao et al., 2018; Gharahkhani et al., 2018; Khawaja et al., 2018; MacGregor et al., 2018; Shiga et al., 2018).