To explore clinical correlation between ERβ and antitumor immunity, we used a bioinformatics tool (TIMER) to assess tumor-immune correlations in human tumor samples.19 Several solid cancer types display significant positive correlation between ERβ mRNA levels and genes associated with antitumor immunity including CD4, CD8A and GZMB (online supplemental figure S8A-C). The gene discussed is CD8A; the disease is neoplasm.