After 21 days, we examined the routine blood parameters and found that the LLC-bearing mice developed normocytic anemia: hemoglobin (Hb) and RBC levels decreased significantly, while the mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) remained normal (Fig. 1a–e). The gene discussed is GSTM1; the disease is anemia.