For M0 ccRCC patients, expression of VEGFR2, NRP2, VEGFC, VEGFR3, PLXA2 above their respective best cut off was of good prognosis for DFS (trend (T, p between 0.08 and 0.06) for NRP2, VEGFC) and significant (S) for VEGFR2, VEGFR3, PLXA2). The gene discussed is NRP2; the disease is nonpapillary renal cell carcinoma.