Until recently, growing evidence highlights the role of TMEM106B in other neurological processes including hippocampal sclerosis of aging [32], neuronal loss [31], cognitive deficits [31], better residual cognition [30], AD [9, 33], Parkinson’s disease [34], and amyotrophic lateral sclerosis [34]. The gene discussed is TMEM106B; the disease is Parkinson disease.