The ratio between antiangiogenic biomarkers such as soluble FMS-like tyrosine kinase-1 (sFLT1) and angiogenic markers such as placental growth factor (PLGF) was demonstrated to usefully predict preeclampsia in gestations complicated by hypertension and the need for more or less urgent action.27,67,88,89. This evidence concerns the gene FLT1 and hypertensive disorder.