Protein levels of collagen I, vimentin, TGF-β, p-GSK-3β and active-β-catenin were significantly upregulated by myocardial overexpression of FGF23 in CRS mice compared with the MI alone or sham ones, which were suppressed by PD173074 treatment (Figure 4E, 4F). Here, GSK3B is linked to congenital rubella syndrome.