The phenotypes include (i) the cell abundances of 6 major immune cell types (leukocyte, T cells CD8, activated NK cells, activated dendritic cells, Tregs, macrophages M2), which were deconvoluted from tumor transcriptome, (ii) the neoantigen number predicted from SNVs and Indels, (iii) TCR richness inferenced from tumor RNA-Seq and (iv) the TIL regional fraction estimated from the tissue image. The gene discussed is CD8A; the disease is neoplasm.