SMC3 was found to be overexpressed in synovial sarcoma (by 5.206-fold in the Detwiller dataset) In the Barretina datasets, SMC4 was overexpressed in lieomyosarcoma, pleomorphic liposarcoma, myxofibrosarcoma, dedifferentiated liposarcoma and myxoid/round cell liposarcoma compared to normal samples (5.750-, 4.898-, 4.866-, 3.671- and 2.839-fold increases, respectively). The gene discussed is SMC4; the disease is pleomorphic liposarcoma.