To demonstrate that the axis that MIR4435‐2HG promoted KLF6 expression by sponging to miR‐513a‐5p in ccRCC, we designed a rescue experiment to reveal the role of MIR4435‐2HG/miR‐513a‐5p/KLF6 axis in ccRCC. Here, KLF6 is linked to nonpapillary renal cell carcinoma.