Furthermore, the activation of an atypical pattern of interferon downstream signaling, involving both interferon (IFN)‐gamma‐ and IFN‐alpha‐responsive genes, was detected in the cerebellum of the Niemann‐Pick disease type C1 mouse model, resulting in the elevation of IFN‐gamma‐responsive cytokines (Shin et al, 2019). This evidence concerns the gene IFNG and Niemann-Pick disease, type C1.