Gao et al. [36] found that autocrine CXCL5/CXCR2 signaling could promote the migration and invasion of bladder cancer cells, while Zhou et al. [20] revealed that autocrine CXCL5/CXCR2 signaling could enhance epithelial–mesenchymal transition in hepatocellular carcinoma cells. Here, CXCR2 is linked to hepatocellular carcinoma.