BM-residing GP33-specific TEM cells expressing high levels of KLRG1 and CX3CR1 were abundantly present in MCMV-GP33-infected mice and moderately existing after LCMV Armstrong infection (BM cluster 1), whereas a Ly6ChighCD127+CXCR3+ TEM cell subset (BM cluster 6) associated uniquely to LCMV Armstrong and a Sca-1highCD38+CD27+TEM cell subset (BM cluster 10) was mainly present upon MCMV-GP33 infection. The gene discussed is CX3CR1; the disease is infection.