Two recent reports demonstrate that the expression of ACE2, furin, and NRP1 or NRP2 augments SARS-CoV-2 cellular infection and that this is a likely mechanism through which SARS-CoV-2 infects the olfactory epithelium.13,19 Because ACE2 is a secreted protein that shows diffuse staining in hDRG (Fig. 3C) and furin and NRP1 are likely expressed by many nociceptors,64,76 this increases the probability that the virus may infect these cells. This evidence concerns the gene ACE2 and infection.