Since the TNM stage contains T, N, and M stages and tumor-infiltrating immune cells contain CD4, CD8, and FoxP3, we entered TNM stage, CD4, and the FoxP3/CD8 ratio [29] into the multivariate analysis, which revealed one tumor characteristic (TNM stage (p = 0.003)) and three immune variables (PD-L1 (p = 0.014), CD4 (p = 0.030), and FoxP3/CD8 (p = 0.044)) that were independent indicators for overall survival and were thereby included in the following predictive model (Table 2). Here, CD274 is linked to neoplasm.