•MNTs with epidermal growth factor (EGF) as a ligand module(MHTEGF), which exhibit specificity with respect to cells (Examples:cells of bladder cancer, head and neck cancer, glioblastoma, and colorectalcancer [17, 18]) overexpressing epidermal growth factor receptors (EGFR)[9, 19, 20],. This evidence concerns the gene EGFR and glioblastoma.