Elevated circulating levels of C-reactive protein (CRP) as well as tumor necrosis factor-alpha (TNF-α), interleukin- (IL-) 1β, IL-6, and IL-1 receptor antagonist (ra) in T2DM have been described in several cross-sectional and prospective studies [6–8]. The gene discussed is IL6; the disease is type 2 diabetes mellitus.