Because CPR, TNF-α, and IL-6 are important inflammatory factors affecting the T2DM disease process [17] and the data of other inflammatory factors were insufficient, so the aim of this meta-analysis was to systematically summarize the evidence of the effects of exercise on the levels of CRP, TNF-α, and IL-6 in adults with type 2 diabetes. Here, TNF is linked to type 2 diabetes mellitus.