A positive correlation between KYN, 3-HKYN, AA, and QA with crucial factors associated with the development of atherosclerosis such as TF, von Willebrand factor (vWF), thrombomodulin, and prothrombin fragments F(1+2) concentration as well as sICAM-1 (soluble intercellular adhesion molecule-1) and sVCAM-1 (soluble circulating vascular cell adhesion molecule-1) level was noticed [114, 133, 138, 139]. Here, VCAM1 is linked to atherosclerosis.