An antioxidant and an important component of the electron transport chain, coenzyme Q10 (CoQ10), has an effect on biomarkers of inflammation and oxidative stress, and the study found that CoQ10 significantly increased SOD and catalase (CAT) levels in CAD patients, significantly reduced MDA and dienes, and had significant effect on C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and GPx levels [142]. The gene discussed is TNF; the disease is coronary artery disorder.