In their work, Samakova et al. combined insights into the phosphatidylinositol-3-kinase- (phosphoinositide-3-kinase-) protein kinase B (serine-threonine protein kinase) (PI3k/Akt) pathway and the association with oxidative stress, angiogenesis, and mesenchymal stem cell survival in pathophysiologic conditions in ischemia [260]. Here, AKT1 is linked to ischemia.