MAP2K7 and non-small cell lung carcinoma: We confirmed the inhibitory effect of Evo on the expression of Akt, MEK, and Src and their active (phosphorylated) forms in both CSC and non-CSC populations in NSCLC (H1299, H460), colon (HCT116), and breast (MDA-MB-231) cancer cells (Figure 3F, S9).